Glutathione: The Skincare Ingredient You Need to Know About

Skincare benefits of Glutathione
@tarafalla | @nadineleopold

In the ever-evolving world of skincare, where powerhouse actives like hyaluronic acid, vitamin C, niacinamide, and retinol dominate the conversation, a lesser-known ingredient is quietly gaining traction: glutathione. This potent antioxidant offers a wide range of skincare benefits, making it a valuable addition to any skincare routine. To uncover glutathione’s potential, we’ve consulted top skincare experts to explain what it is, how it works, and how it can transform your skin.

What is glutathione?

Glutathione is a naturally occurring molecule in our bodies, composed of glycine, glutamic acid, and cysteine. “It is extremely beneficial to us – its main purpose is to protect the cells of our bodies from harmful toxins,” explains Kelly Saynor, aesthetic nurse and founder of Prfkt. Considered by some to be the ‘master antioxidant’, glutathione plays a crucial role in shielding cells from oxidative stress. As Kimberley Medd, Head of Clinic at Face the Future, notes, “It works to neutralise free radicals, which can accelerate the ageing process and contribute to a range of skin issues, including dullness, pigmentation, and fine lines.”

How does glutathione benefit the skin?

As we age, our glutathione levels naturally decline, contributing to visible signs of ageing such as wrinkles and loss of skin elasticity. “Replenishing glutathione, whether through topical applications or supplements, helps to slow this decline and promote a more youthful complexion,” explains Kelly Saynor.

Jo Corcoran, UK Head of Education at Image Skincare, adds, “Applying glutathione topically helps to repair and rebuild the skin, making it an excellent ingredient for treating wrinkles, acne, and detoxifying the skin.”

Furthermore, glutathione can brighten and even out skin tone by reducing melanin production. Kimberley Medd notes that it also “supports the skin’s natural regeneration process, leading to a smoother, more youthful complexion.”

Which skin types benefit most from glutathione?

Glutathione is a versatile ingredient suitable for most skin types, particularly those with hyperpigmentation, uneven skin tone, or signs of ageing. “Every skin will benefit from glutathione as everybody experiences oxidative damage, but it is particularly beneficial for those concerned with ageing, acne, or hyperpigmentation and post-hyperpigmentation spots,” explains Corcoran.

Kimberley Medd adds, “Its ability to brighten the skin and reduce the appearance of dark spots makes it a great option for anyone looking to improve their complexion and revive dull or tired-looking skin.” Medd further notes that even sensitive skin types can usually tolerate glutathione well due to its gentle and non-irritating nature.

How does glutathione interact with active ingredients, such as retinoids, vitamin C, and AHAs?

Glutathione works well with many active ingredients, enhancing their effects without causing irritation. According to Medd, “When used alongside retinoids, it can help mitigate potential dryness and irritation while boosting the overall anti-ageing benefits. Combined with vitamin C, glutathione creates a powerful antioxidant duo that brightens and evens skin tone. With AHAs, glutathione supports the exfoliation process by encouraging cell turnover and skin regeneration, helping to reveal a smoother, more luminous complexion.”

How can I incorporate glutathione into my skincare routine?

You can incorporate glutathione into your skincare routine in a few different ways. “Use skincare products formulated with glutathione to directly target skin health,” advises Saynor. She also recommends oral supplements, noting, “Taking glutathione supplements can not only support your skin but also boost your immune system and overall wellness.” Additionally, including glutathione-rich foods like broccoli, avocados, garlic, spinach, walnuts, asparagus, turmeric, and okra in your diet can naturally elevate your body’s glutathione levels, contributing to healthier skin from within.

Continue scrolling to discover the glutathione-inclusive skincare products worth investing in.

Image Vital C Hydrating Facial Mist

Infused with stabilised vitamin C, gold sub-microparticles, sugarcane extract, orange peel oil, and glutathione, this lightweight mist delivers hydration, shields against environmental stressors and free radicals, retains moisture, and provides an immediate boost of radiance.

Perricone MD Essential Fx Acyl-Glutathione Chia Oil

Combining the skin-rejuvenating properties of glutathione with the nourishing benefits of chia seed oil, this facial oil is ideal for those seeking deep hydration and antioxidant protection. Not only does it hydrate and nourish the skin, but it also enhances its resilience and delivers a gorgeous glow.

Dr. David Jack Good Night

This overnight repair cream features a blend of granactive retinoid and niacinamide to stimulate collagen production, reduce hyperpigmentation, and prevent breakouts. Ingredients such as polyhydroxy acids, vitamin B5, vitamin E, glutathione, and hyaluronic acid work to brighten, heal, and nourish the skin.

Prfkt Pep Talk Instant Mask Peel

The perfect pick me up for any complexion, this at-home peel combines BHAs with AHAs to deeply exfoliate the skin to brighten the complexion and improve texture. It’s fortified with antioxidants like 3-O-ethyl ascorbic acid, glutathione, retinol, and vitamin E to promote cell turnover and collagen production, while aloe vera, green tea, and grape seed provide soothing and nourishing benefits.

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